Cytochrome P-450 CYP11B1

《英文msh詞典》Cytochrome P-450 CYP11B1
[同義詞] Cytochrome P-450 CYP11B1
[主題詞] Steroid 11-beta-Hydroxylase
[中文釋義] 細胞色素 P450 CYP11B1
[英文釋義] A mitochondrial cytochrome P450 enzyme that catalyzes the 11-beta-hydroxylation of steroids in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme,encoded by CYP11B1 gene,is important in the synthesis of CORTICOSTERONE and HYDROCORTISONE. Defects in CYP11B1 cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA,CONGENITAL).